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dc.contributor.authorAbaci A.
dc.contributor.authorAtas A.
dc.contributor.authorUnuvar T.
dc.contributor.authorDemir K.
dc.contributor.authorBober E.
dc.contributor.authorBüyükgebiz A.
dc.date.accessioned2019-08-13T12:10:23Z
dc.date.accessioned2019-08-13T15:53:32Z
dc.date.available2019-08-13T12:10:23Z
dc.date.available2019-08-13T15:53:32Z
dc.date.issued2009
dc.identifier.issn0334018X
dc.identifier.urihttps://dx.doi.org/10.1515/JPEM.2009.22.6.539
dc.identifier.urihttp://hdl.handle.net/11446/1959
dc.descriptionPubMed ID: 19694201en_US
dc.description.abstractAim: To compare the long-term outcomes of continuous subcutaneous insulin infusion (CSII) pump therapy with the clinical and metabolic parameters recorded during multiple daily insulin (MDI) therapy. Patients and Methods: CSII pump was used by volunteer adolescents, who had a duration of diabetes mellitus (DM) longer than one year, regularly attended periodic examinations for the last year, measured and recorded blood glucose levels on average 3 to 4 times a day, and did not achieve the preferred metabolic control even though the use of MDI therapy. Carbohydrate counting and flexible MDI therapy was taught to these patients before CSII pump implantation. The metabolic and clinical parameters of the patients for the post-CSII pump period were compared with the data of flexible and non-flexible MDI periods. Results: The mean CSII pump implantation age of the 17 adolescents enrolled in the study was 15.53 ± 1.8 years, duration of DM 6.77 ± 4.05 years, flexible MDI injection duration 0.70 ± 0.20 years, and duration of CSII pump use 2.07 ± 1.12 years. A decrease was detected in HbA1c levels of the patients with transition to CSII pump compared to flexible and non-flexible MDI injection periods; however, this decrease was not statistically significant (7.71%, 8.21%, and 8.71%, respectively, p = 0.105). No statistically significant difference was detected in frequency of hypoglycemia, lipid profiles, total daily insulin requirement, and BMI SDS values of the patients when data of the post-CSII pump state were compared with that of flexible and non-flexible MDI therapy groups. Conclusion: In adolescents, it was found that CSII pump therapy is efficient and safe without any increased risk for weight gain and hypoglycemia compared to flexible and non-flexible MDI injection periods. The present study also demonstrated that flexible MDI injection therapy might be efficiently and safely used in patients who cannot receive CSII pump therapy due to social and/or financial factors. © Freund Publishing House Ltd.en_US
dc.language.isoengen_US
dc.publisherFreund Publishing House Ltden_US
dc.relation.isversionof10.1515/JPEM.2009.22.6.539en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdolescentsen_US
dc.subjectInsulin pump treatmenten_US
dc.subjectType 1 diabetes mellitusen_US
dc.titleA comparison of multiple daily insulin therapy with continuous subcutaneous insulin infusion therapy in adolescents with type 1 diabetes mellitus: A single-center experience from Turkeyen_US
dc.typearticleen_US
dc.relation.journalJournal of Pediatric Endocrinology and Metabolismen_US
dc.contributor.departmentDBÜen_US
dc.identifier.issue6en_US
dc.identifier.volume22en_US
dc.identifier.startpage539en_US
dc.identifier.endpage545en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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