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dc.contributor.authorSinangil, Ayse
dc.contributor.authorCelik, Vedat
dc.contributor.authorBarlas, Soykan
dc.contributor.authorKoc, Yener
dc.contributor.authorBasturk, Taner
dc.contributor.authorSakaci, Tamer
dc.contributor.authorEcder, Tevfik
dc.date.accessioned2019-08-13T12:10:23Z
dc.date.accessioned2019-08-13T15:56:31Z
dc.date.available2019-08-13T12:10:23Z
dc.date.available2019-08-13T15:56:31Z
dc.date.issued2017
dc.identifier.issn0211-6995
dc.identifier.issn1989-2284
dc.identifier.urihttps://dx.doi.org/10.1016/j.nefro.2016.11.022
dc.identifier.urihttp://hdl.handle.net/11446/2325
dc.descriptionWOS: 000400322000009en_US
dc.descriptionPubMed ID: 28262264en_US
dc.description.abstractAim: New-onset diabetes after transplantation (NODAT) is a frequent metabolic complication and is considered a risk factor for patients undergoing renal transplant. The aim of this study was to evaluate the incidence and developing duration of new-onset diabetes after transplant (NODAT) and influencing factors. Methods: All patients' data was investigated retrospectively. Diabetics, follow-up period < 6 months, age < 18years were excluded. Demographic, clinical and laboratory data was recorded. Patients were divided into two groups: with/without NODAT. NODAT group was divided into four subgroups according to the time of developing NODAT, which were 0-3, 3-6, 6-12 and 12 months later. Two groups were compared, to investigate the incidence of NODAT and risk factors associated with the occurrence of NODAT. Results: We retrospectively analyzed the records of 570 patients, of which 420 patients were included. Seventy (16.6%) patients had NODAT (36 female, mean age 51.7 +/- 8.2 years, mean follow-up 41.6 +/- 21.5 months), 52.8% of patients developed NODAT within the first three months of being diagnosed. 350 patients (116 female, mean age 43.2 +/- 12.5 years, mean follow-up 41.6 21.5 months) were without NODAT. The incidence of impaired fasting glucose (IFG) during the first week after transplant was found to be higher in the patients with NODAT (p <0.001). There was positive correlation between NODAT and older age, obesity, family history of diabetes, presence of IFG, fasting plasma glucose, total and LDL-cholesterol, triglycerides, parathormone. Old age, obesity, presence of IFG, pretransplant hypertriglyceridemia and hyperparathyroidism were predictors of development of NODAT. Conclusion: Incidence of NODAT, especially the first six months, was high. All patients should be screened for IFG within the first week. Patients with dyslipidemia, elderly and obese patients should be closely monitored for the risk of development of NODAT. (C) 2017 Sociedad Espanola de Nefrologia. Published by Elsevier Espana, S.L.U.en_US
dc.language.isoengen_US
dc.publisherSOC ESPANOLA NEFROLOGIA DR RAFAEL MATESANZen_US
dc.relation.isversionof10.1016/j.nefro.2016.11.022en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPTDMen_US
dc.subjectRenal transplantationen_US
dc.subjectImpaired fasting glucoseen_US
dc.titleThe incidence of new onset diabetes after transplantation and related factors: Single center experienceen_US
dc.typearticleen_US
dc.relation.journalNEFROLOGIAen_US
dc.contributor.departmentDBÜen_US
dc.identifier.issue2en_US
dc.identifier.volume37en_US
dc.identifier.startpage181en_US
dc.identifier.endpage188en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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