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dc.contributor.authorCatli, Gonul
dc.contributor.authorAbaci, Ayhan
dc.contributor.authorAltincik, Ayca
dc.contributor.authorDemir, Korcan
dc.contributor.authorCan, Sule
dc.contributor.authorBuyukgebiz, Atilla
dc.contributor.authorBober, Ece
dc.date.accessioned2019-08-13T12:10:23Z
dc.date.accessioned2019-08-13T16:03:23Z
dc.date.available2019-08-13T12:10:23Z
dc.date.available2019-08-13T16:03:23Z
dc.date.issued2012
dc.identifier.issn0334-018X
dc.identifier.issn2191-0251
dc.identifier.urihttps://dx.doi.org/10.1515/jpem-2012-0130
dc.identifier.urihttp://hdl.handle.net/11446/3072
dc.descriptionWOS: 000312159700013en_US
dc.descriptionPubMed ID: 23329759en_US
dc.description.abstractHyperprolactinemia is a rare endocrine disorder in childhood, which may result from hypophyseal adenoma. We aimed to review the etiologic reasons and clinical features in hyperprolactinemia patients retrospectively. The mean age of 11 female patients at diagnosis was 14.2 +/- 1.3 years. Five patients had microadenoma, four patients had macroadenoma, and two patients were diagnosed with idiopathic hyperprolactinemia. The most frequent symptoms were menstrual disorders, headache, and galactorrhea, and one-third of the patients had obesity at diagnosis. There was no anterior pituitary hormone deficiency. All patients received bromocriptine as initial therapy; only two patients with macroadenoma and one patient with microadenoma were switched to cabergoline. Transsphenoidal surgery was performed for a patient with macroadenoma, who had cavernous sinus invasion and visual field defect. Medical treatment should be the first-line treatment option in both microadenoma and macroadenoma cases without any neurological signs. Surgery should be employed with limited indications.en_US
dc.language.isoengen_US
dc.publisherWALTER DE GRUYTER GMBHen_US
dc.relation.isversionof10.1515/jpem-2012-0130en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbromocriptineen_US
dc.subjectcabergolineen_US
dc.subjectchildhooden_US
dc.subjecthyperprolactinemiaen_US
dc.subjectprolactinomaen_US
dc.titleHyperprolactinemia in children: clinical features and long-term resultsen_US
dc.typearticleen_US
dc.relation.journalJOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISMen_US
dc.contributor.departmentDBÜen_US
dc.identifier.issue11.Araen_US
dc.identifier.volume25en_US
dc.identifier.startpage1123en_US
dc.identifier.endpage1128en_US
dc.contributor.authorID0000-0002-1812-0321en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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