Advanced Search

Show simple item record

dc.contributor.authorIgdem, S.
dc.contributor.authorErcan, T.
dc.contributor.authorAlco, G.
dc.contributor.authorZengin, F.
dc.contributor.authorOzgules, R.
dc.contributor.authorGeceer, G.
dc.contributor.authorTurkan, S.
dc.date.accessioned2019-08-13T12:10:23Z
dc.date.accessioned2019-08-13T16:05:11Z
dc.date.available2019-08-13T12:10:23Z
dc.date.available2019-08-13T16:05:11Z
dc.date.issued2009
dc.identifier.issn0392-2936
dc.identifier.urihttp://hdl.handle.net/11446/3444
dc.descriptionWOS: 000270030600019en_US
dc.descriptionPubMed ID: 19899413en_US
dc.description.abstractPurpose: Before initiating an intensity modulated radiotherapy (IMRT) program for gynecologic malignancies we prospectively evaluated the potential benefits of IMRT by dose volume histogram comparison of IMRT and 3D conformal radiotherapy plans. Methods: Plans of ten consecutive patients with cervical and endometrial cancer were evaluated. For each patient a 4-field box technique was compared to an IMRT plan. Both plans were normalized to deliver 50.4 Gy to the PTV in six patients and 45 Gy in the remaining four. Isodose distributions and dose volume histograms were compared in seven dose levels. Results: IMRT reduced the volume of small bowel receiving more than 45 Gy in all patients. The average absolute volume of small bowel receiving 45 Gy was significantly reduced from 318 cc to 33 cc. No significant increase in the volume of small bowel receiving less than 20 Gy was observed. Rectum, bladder and bone marrow volumes receiving high doses were also significantly reduced with IMRT. Conclusions: IMRT significantly reduces the volume of normal tissues irradiated to high doses Without compromising the target coverage. This may potentially lead to a reduction in treatment related toxicities.en_US
dc.language.isoengen_US
dc.publisherI R O G CANADA, INCen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPelvic IMRTen_US
dc.subjectGynecologic Malignanciesen_US
dc.subjectOrgan sparingen_US
dc.titleDosimetric comparison of intensity modulated pelvic radiotherapy with 3D conformal radiotherapy in patients with gynecologic malignanciesen_US
dc.typearticleen_US
dc.relation.journalEUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGYen_US
dc.contributor.departmentDBÜen_US
dc.identifier.issue5en_US
dc.identifier.volume30en_US
dc.identifier.startpage547en_US
dc.identifier.endpage551en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record