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dc.contributor.authorMen, Ebubekir Emre
dc.contributor.authorYildirimturk, Ozlem
dc.contributor.authorTugcu, Aylin
dc.contributor.authorAytekin, Vedat
dc.contributor.authorAytekin, Saide
dc.date.accessioned2019-08-13T12:10:23Z
dc.date.accessioned2019-08-13T16:05:20Z
dc.date.available2019-08-13T12:10:23Z
dc.date.available2019-08-13T16:05:20Z
dc.date.issued2008
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.urihttp://hdl.handle.net/11446/3470
dc.descriptionWOS: 000256807300006en_US
dc.descriptionPubMed ID: 18524727en_US
dc.description.abstractObjective: Atrial fibrillation (AF) is one of the most frequent complications that may occur after open-heart surgery. Clinical reports regarding comparison of different anti-arrhythmic agent's usage to maintain,sinus rhythm after open-heart surgery are not conclusive. We examined the effects of different anti-arrhythmic agents administration before operation on postoperative AF incidence, duration of hospitalization and complications. Methods: Overall, 180 patients (130 men and 50 women, mean age 58.13 +/- 11.71 years) who were candidates for open-heart surgery, were included in this prospective, single-blind study. All patients divided into five different groups. All anti-arrhythmic drugs were administered approximately 7 days before the operation. Propafenone was given to Group 1 (G1); sotalol to Group 2 (G2); amiodarone to Group 3 (G3) and diltiazem to Group 4 IN) at doses of 300 mg/day, 80 mg/day, 400 mg/day and 180 mg/day orally respectively. The fifth group (G5) did not receive any of anti-arrhythmic drugs. The medication was continued for ten days postoperatively. Statistical analysis was performed using Chi-Square and one-way ANOVA tests. Results: Atrial fibrillation developed during postoperative period in 18.1% patients in G1, 9.1% patients in G2, 16.2% patients in G3, 28.6% patients in G4 and 38.1 % patients in G5. The prevalence of postoperative AF was significantly higher in G5 as compared with other groups (p=0.026). There were significant differences across groups in duration of hospitalization (p=0.033), with shortest mean duration of hospitalization in G2 (8.9 +/- 2.7 days). Conclusion: Any anti-arrhythmic agent started 7 days before the operation and continued for 10 days, may reduce the prevalence of postoperative AF, morbidity and duration of hospitalization. However, we found that sotalol and amiodarone were more effective than other anti-arrhythmic agents in our patient population.en_US
dc.language.isoturen_US
dc.publisherTURKISH SOC CARDIOLOGYen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectatrial fibrillationen_US
dc.subjectopen heart surgeryen_US
dc.subjectanti-arrhythmic drugsen_US
dc.titleThe comparison between the efficiency of different anti-arrhythmic agents in preventing postoperative atrial fibrillation after open heart surgeryen_US
dc.typearticleen_US
dc.relation.journalANATOLIAN JOURNAL OF CARDIOLOGYen_US
dc.contributor.departmentDBÜen_US
dc.identifier.issue3en_US
dc.identifier.volume8en_US
dc.identifier.startpage206en_US
dc.identifier.endpage212en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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